It is a kind of organic antipyretic and antispasmodic compound, mainly soluble in water-soluble ethyl phenol and o5so6, which is a kind of organic antipyretic and antispasmodic compound, mainly used in water-soluble and anti-inflammatory organic solvents such as water-soluble ethyl ether and o5so6. It mainly comes from the rhizome of ginger plant kaempferol galanga L and widely exists in various fruits, vegetables and beverages. Its pure products have been extracted from tea, broccoli, witch hazelnut, propolis, grapefruit and other green plants. It has attracted extensive attention because of its anti-cancer, anti-inflammatory, anti-oxidation, antibacterial, anti-virus and other effects. Kaempferol also belongs to flavonoids, and its structure is similar to kaempferol, but they can not be classified as the same substance. On October 27, 2017, the list of carcinogens published by the international agency for research on cancer of the World Health Organization was preliminarily sorted for reference. Kaempferol was included in the list of class 3 carcinogens.
Function：
Cancer prevention and anticancer
Kaempferol is the most common flavonoid, and long-term diet will reduce the risk of cancer. Studies have reported that high intake of kaempferol can reduce the recurrence of advanced colorectal adenomas, and compared with other dietary flavonoids, high Iyama Na can significantly reduce the risk of pancreatic cancer. The latest research shows that kaempferol can also inhibit hepatocyte growth factor (HGF) and its receptor tyrosine protein kinase related to the growth and metastasis of medulloblastoma in children. Therefore, this disease can be prevented and treated by dietary kaempferol.
Anti infection and anti inflammation
Xu et al. Showed that kaempferol had good antibacterial activity and also had an effect on methicillin resistant Staphylococcus aureus (MRSA). K-br disk method showed that the concentration of 50 mg / tablet could make the antibacterial circle of MRSA up to 8.5mm, and it also had good antibacterial activity against Vibrio cholerae and Enterococcus faecalis. In the aspect of antiviral, kaempferol can inhibit in a concentration - dependent manner at non - cytotoxic concentration
In terms of anti-inflammatory, kaempferol achieves anti-inflammatory effect mainly by inhibiting the expression of inflammatory factors.
Prevention and treatment of diabetes Atherosclerosis (as) is a chronic inflammatory disease of vascular wall. Studies have shown that kaempferol can not only inhibit the oxidation of low density lipoprotein (LDL) induced by copper ion to oxidized low density lipoprotein (ox LDL), but also reduce the expression of CD 36 protein on the surface of THP-1 macrophages and prevent the uptake of ox LDL by THP-1 macrophages, So as to prevent the occurrence of atherosclerosis. The incidence rate of diabetes is hitherto unknown. Studies have shown that kaempferol can act as an agonist with the hypoglycemic drug rosiglitazone, but its adverse reactions are much weaker than rosiglitazone. It can increase the glucose uptake of 3T3-L1 cells without affecting adipogenesis, indicating that it is expected to become a new generation of insulin sensitizer.
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