Bupivacaine is a local anesthetic, belonging to the ester group of local anesthetics. It is widely used in surgery and pain management to provide long-lasting and effective pain relief. The chemical name of Bupivacaine is 1-butyl-N - (2,6-dimethylphenyl) piperidine-2-carboxamide, and the molecular formula is C18H28N2O. It is a white crystalline solid that is soluble in water and ethanol.
Bupivacaine produces anesthesia by blocking neural transmission. It mainly acts on voltage gated sodium channels near nerve terminals, preventing the conduction of nerve impulses. This effect leads to an obstruction in the depolarization of nerve cells, thereby inhibiting the transmission of sensory and pain signals.
| Name | Bupivacaine |
| CAS No | 2180-92-9 |
| Appearance | White Crystalline powder |
| Molecular Formula | C18H28N2O |
| Molecular Weight | 288.43 |
| Assay | 99% Bupivacaine |
(1). Surgical anesthesia: Bupivacaine is commonly used for local anesthesia in various surgical processes. It can provide anesthesia effect through local infiltration anesthesia or nerve block, making the surgical area painless.
(2). Delivery analgesia: Bupivacaine is commonly used for the purpose of analgesia during delivery. Lumbar or epidural anesthesia is the most common application method that can provide long-term analgesic effects.
(3). Pain management: Bupivacaine is widely used to treat chronic pain, such as neuralgia, muscle pain, arthritis pain, etc. It can be administered by local injection or patch, and provides long-lasting pain relief.
(4). Nerve block: Bupivacaine can be used for nerve block, by blocking the conduction around specific nerves, to diagnose and treat certain nerve related diseases such as facial paralysis, neck and back pain.
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