Mirtazapine (brand names: Avanza, Axit, Calixta, Mirtaz, Mirtazon, Remeron, Zispin) is an atypical antidepressant with noradrenergic and specific serotonergic activity. It blocks the α2 adrenergic auto- and heteroreceptors (enhancing serotonin release), and selectively antagonizes the 5-HT2 serotonin receptors in the central and peripheral nervous system. It also enhances serotonin neurotransmission at the 5-HT1 receptor and blocks the histaminergic (H1) and muscarinic receptors. Mirtazapine is not a serotonin or norepinephrine reuptake inhibitor but may increase serotonin and norepinephrine by other mechanisms of action.
Product Name: Mirtazapine Anhydrous Powder
Extract solvents: Ethanol & water
Mesh: 100% pass 80 mesh
Appearance: white fine powder
Specifications: 99%
CAS:85650-52-8
Molecular formula:C17H19N3
Molecular Weight: 265.35
(1). Depression: Mirtazapine is a common drug used to treat depression. It is suitable for various types of depressive disorders, including mild, moderate, and severe depressive disorders, as well as monophasic and bipolar depressive disorders.
(2). Anxiety disorder: Mirtazapine is also widely used in the treatment of anxiety disorder because of its sedative and anti anxiety effects. It is particularly suitable for anxiety patients with insomnia and decreased appetite.
(3). Insomnia: Mirtazapine can help improve insomnia, especially effective for patients with difficulty in falling asleep and waking up early. Its sedative effect helps to stabilize sleep and improve the quality of sleep for patients.
Nightmares and post-traumatic stress disorder: Mirtazapine has shown certain effects in the treatment of nightmares and post-traumatic stress disorder. It can reduce the frequency of nightmares and improve sleep quality, thereby alleviating related psychological symptoms.
(4). Clinical nutrition support: because Mirtazapine can promote appetite and weight gain, it is often used for clinical nutrition support, especially for the treatment of anorexia and emaciation.
(1). Antidepressant effect: Mirtazapine relieves depressive symptoms by increasing the release and signal transduction of neurotransmitters such as glutamic acid and 5-hydroxytryptamine. It can improve depression symptoms such as depression, anxiety, and insomnia, and has the characteristic of quickly exerting its effects.
(2). Sedative effect: The antagonism of Mirtazapine on histamine H1 receptor leads to sedative and hypnotic effects. Therefore, it can be used to treat anxiety and insomnia.
(3). Appetite increasing effect: different from other antidepressants, Mirtazapine can improve the nutritional status of patients by increasing appetite and promoting weight gain.
(4). Psychological activity: Mirtazapine also has some psychological activity, such as increasing social interaction, improving self-esteem and relieving tension.
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