Corosolic acid is derived from the extract of crape myrtle. The experimental results in vivo and in vitro showed that corosolic acid promoted the absorption and utilization of glucose by stimulating the transport of glucose, so as to achieve its hypoglycemic effect. The excitatory effect of corosolic acid on glucose transport is similar to that of insulin. Therefore, corosolic acid is also known as plant insulin.
1.English Name: corosolic acid
2. Molecular formula: c30h48o4
3. molecular weight 472.7
4. CAS No：4547-24-4
5. Source: extract of crape myrtle (commonly known as Barnabas, which is rich in the Philippines).
6.Specifications: corosolic acid 2%, corosolic acid 3%, corosolic acid 20%, corosolic acid 30%, corosolic acid - 98% HPLC
Pharmacological action
The excitatory effect of corosolic acid on glucose transport is similar to that of insulin. Therefore, corosolic acid is also known as plant insulin. The results of animal experiments showed that corrosuo acid had significant hypoglycemic effects on normal rats and diabetic mice. Corosolic acid also has the effect of weight loss. Clinical studies have found that after taking the drug, it can regulate the content of insulin and blood glucose in the body, with an obvious trend of weight loss (monthly average weight loss of 0.908-1.816Kg). The process is relatively slow and there is no need to go on a diet. Corosolic acid also has many other biological activities. For example, it has a significant inhibitory effect on TPA induced inflammatory response, and its anti-inflammatory effect is stronger than that of commercial anti-inflammatory drug indomethacin; It also has DNA polymerase inhibitory activity and inhibits the growth of a variety of tumor cells.
At the end of the article, we can recommend some of our company's main products, all of which support OEM/ODM one-stop service. If you have any needs, please feel free to contact us. Our email is: rebecca@tgybio.com.
