Geniposide is a kind of iridoid glucoside, which is easily soluble in water and is the main pharmacodynamic component of Gardenia. Geniposide has significant effects on diseases of digestive system, cardiovascular system and central nervous system. In addition, geniposide has certain anti-inflammatory and soft tissue injury effects.
Pharmacological action: geniposide has the functions of relieving diarrhea, analgesia, cholagogic, anti-inflammatory, treating soft tissue injury, inhibiting gastric juice secretion and reducing pancreatic amylase. Geniposide has many uses. Fermentation of different conditions can be made into natural food coloring agent gardenia blue and gardenia red. It is also used as raw material for the treatment of cardiovascular and cerebrovascular diseases, liver and gallbladder diseases and diabetes.
Geniposide is a kind of iridoid glucoside, which is easily soluble in water. It is the main pharmacodynamic component of gardenia, and the content is about 3% - 8% depending on the place of origin. Geniposide can be β- Glucosidase hydrolyzes to genipin. Modern studies have shown that geniposide has significant effects on diseases of digestive system, cardiovascular system and central nervous system. In addition, geniposide has certain anti-inflammatory and soft tissue injury effects. Geniposide is also widely used in other fields besides medicine, such as plant yield increasing agent, biological detection agent and so on.
The extraction method of Geniposide generally adopts chloroform, absolute ethanol and other organic solvents to extract in Soxhlet extraction bottle to obtain the total active component Geniposide in Gardenia, which is separated on silica gel column, eluted with a certain proportion of methanol and chloroform mixture, and the eluent is recrystallized in acetone to obtain geniposide crystal, Generally, about 4.0g geniposide can be isolated from 100g gardenia fruit.
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