Chondroitin sulfate (CS) are a class of proteins that form covalent linkages with chondroitin sulfate. Chondroitin sulfate is widely distributed in the extracellular matrix and cell surface of animal tissues. The sugar chain is polymerized by alternating glucuronic acid and N-acetylgalactosamine, and connected to the serine residue of core protein through a sugar like link region. Although the main chain structure of Polysaccharide is not complex, it shows a high degree of heterogeneity in terms of the degree of sulfation, sulfate group and the distribution of the two differences to the re chain of isouronic acid. The fine structure of chondroitin sulfate determines the functional specificity and interaction with a variety of protein molecules.
Pharmacological Action
(1) for the treatment of coronary heart disease, chondroitin sulfate has the effect of clarifying lipid. The health food and medicine developed by this material have been used for a long time to prevent coronary heart disease, angina pectoris, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases. Clinical application has not found obvious toxic and side effects, and can significantly reduce the incidence rate and mortality of coronary heart disease.
(2) Improve joint problems chondroitin sulfate combined with glucosamine can promote cartilage regeneration and soften bones. Clinically, as a commonly used drug for the treatment of joint diseases, it can effectively improve joint problems.
(3) Protecting bone chondroitin sulfate can prevent bone calcification, prevent bone chemicalbook from becoming hard and brittle, and promote rigid bones to restore flexibility; In addition, chondroitin sulfate can also reduce the hard and brittle bone contour in a certain range, and effectively improve bone hyperplasia.
(4) Chondroitin sulfate can improve corneal blood circulation, accelerate metabolism, enhance permeability, promote the absorption of osmotic fluid in corneal stroma and the growth of fibers, eliminate inflammation, and protect corneal collagen fibers; Secondly, chondroitin sulfate can improve the water metabolism of corneal tissue, promote the formation of a breathable and water retaining film on the corneal surface, promote the healing of corneal trauma and improve the symptoms of ocular dryness.
Function
1. Chondroitin sulfate is a mucopolysaccharide extracted from animal cartilage. It plays an important role in the prevention and treatment of cardiovascular diseases and joint diseases. It is an important biochemical product in the market.
2, chondroitin sulfate is used as health food or health care medicine for long-term prevention and treatment of coronary heart disease, angina pectoris, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases. It has no obvious toxic and side effects, and can significantly reduce the incidence rate and mortality of patients with coronary heart disease. Long term clinical application has found that lipids such as fat deposited on the walls of arteries and veins can be effectively removed or reduced, which can significantly reduce plasma cholesterol and prevent the formation of atherosclerosis.
3. Chondroitin sulfate chemicalbook is used to treat neuralgia, neurogenic migraine, joint pain, arthritis, scapular joint pain, pain after abdominal surgery, etc.
4. The prevention and treatment of hearing impairment caused by streptomycin and hearing difficulties and tinnitus caused by various noises have achieved remarkable results. 5. It has adjuvant therapeutic effects on chronic nephritis, chronic hepatitis, keratitis and corneal ulcer.
6. In recent years, it has been reported that chondroitin in shark cartilage has antitumor effect. In addition, chondroitin sulfate is also used in cosmetics and wound healing agents. Chondroitin sulfate is an acidic mucopolysaccharide. It is one of the important components in eye tissue. It can promote corneal water metabolism and improve. It is suitable for visual fatigue and dry eye.
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