Silymarin extract takes the dried fruit of Silybum marianum g. as raw material, and the commercial extract is usually standardized to contain 80% of total silymarin.
Extraction Source
Silymarin is an annual or biennial herb, originally born in southern Europe and North Africa. It has been cultivated and used in Europe and Africa for thousands of years. It is a folk medicinal plant. Silymarin is widely used as a drug for the treatment of liver diseases and cardiovascular diseases. Cultivated in North and Northwest China.
Active Ingredient
The whole grass contains flavonoids and fumaric acid; The seeds contain silybin, isosilybin, dehydrogenated silybin, silydianin, silychristin, silybin polymer, cinnamic acid, myristic acid, palmitoleic acid, arachidonic acid, etc.
Pharmacological Action
1. Liver protection
Silymarin is the main active component of liver protection. It has the effect of regeneration, can stimulate the formation of new hepatocytes and improve liver function; At the same time, it can protect hepatocyte membrane, prevent cytotoxin from infiltrating hepatocytes, and improve the recovery ability of membrane structure defect.
2. Oxidation resistance
The phenolic hydroxyl group of silymarin provides hydrogen atom and has strong Antioxidant effect. They have free radical scavenging properties and anti lipid peroxidation activity.
3. Reduce blood lipid
Silybin can inhibit the plasma membrane Ca2 + channel of adult rat cardiomyocytes, inhibit food induced hypercholesterolemia, reduce very low density lipoprotein (VLDL) and low density lipoprotein (LDL), and increase high density lipoprotein (HDL). It can be used in the treatment of cardiovascular diseases.
Clinical efficacy Silymarin extract is mainly used for viral hepatitis, acute and chronic hepatitis, liver cirrhosis, high-fat liver, nutritional and metabolic diseases and cardiovascular diseases.
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