Fluconazole is a new triazole antifungal infection drug, which was successfully developed by Pfizer in the United States for the first time. It has broad-spectrum antifungal effect and is a systemic antifungal product. It has a high inhibitory effect on fungal cytochrome P-450-dependent enzymes. Selective, but also a potent and specific inhibitor of fungal alcohol synthesis. The pharmacological effect of fluconazole is mainly through inhibiting the activity of enzyme 14α-demethylase in the fungal cytochrome P450 enzyme (CYP450 enzyme) system, thus interfering with the synthesis of fungal cell walls. In this way, fluconazole can interfere with the structure and function of fungal cell membranes, leading to fungal death. Fluconazole is used to treat a variety of fungal infections.
| Product name | Fluconazole
|
| CAS no. | 86386-73-4
|
| Molecular Formula | C13H12F2N6O |
| Molecular Weight | 306.27 |
| Brand Name | TGY |
Fluconazole is a fluorinated triazole antifungal drug with a similar antibacterial spectrum to ketoconazole and stronger antibacterial activity than ketoconazole. Its mechanism of action is to inhibit ergosterol synthase, an essential component of fungal cell membranes, block ergosterol synthesis, destroy the integrity of fungal cell walls, and inhibit its growth and reproduction. This product has strong antibacterial activity against Candida albicans, Microsporum, Cryptococcus neoformans, Epidermophyton and Histoplasma capsulatum.
Potassium Iodide is an inorganic salt containing iodine, commonly used to supplement the body's required iodine element. Its main function is to maintain thyroid function, promote the normal synthesis of thyroid hormones, and help maintain healthy metabolism and normal growth and development. Potassium Iodide can also be used as a protective agent to reduce the absorption of radioactive iodine by the thyroid gland in nuclear radiation accidents or emergencies.
Acetaminophen, also known as Paracetamol, is a commonly used over-the-counter analgesic and fever reducing drug. It effectively alleviates mild to moderate pain and reduces fever, and is relatively safe, suitable for all age groups.
Minoxidil Powder, known as 6 - (1-piperidinyl) - 2,4-pyrimidine diamine-3-oxide, is an organic compound with white or almost white crystalline powder. It can directly relax vascular smooth muscle, has a strong role in small artery dilation, reduces peripheral resistance and blood pressure, and has no effect on volume vessels, so it can promote venous reflux. Antihypertensive drugs for refractory, primary or renal hypertension. It is used to prevent fat hair loss and animal husbandry.
Orlistat can be used to lose weight. It reduces weight by preventing the absorption of fat in the digestive tract. Orlistat can help reduce weight and waist circumference, and is suitable for individuals with a BMI of over 30 or 27 and related health issues.
Pyridoxamine dihydrochloride is a derivative of Vitamin B6. It has Antioxidant and anti glycosylation activities, which can help protect the eyes, kidneys, and nervous system from chronic disease damage. In addition, Pyridoxamine Dihydrochloride has also been used in some related research and clinical trials.
Ketoconazole Powder can be used to treat superficial and deep fungal diseases, such as skin and nail tinea, vaginal candidiasis, gastrointestinal fungal infection, as well as systemic infection caused by Candida albicans, Coccidioides, histoplasm, etc.
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