Yeast - β- Dextran is also called dextran. It is a Polysaccharide. It exists in the mucus secreted by some microorganisms during their growth. Modern studies have found that Agaricus blazei contains the most abundant b-Glucan and has high biological activity. Dextran has high molecular weight and is mainly composed of D-glucopyranose α, The 1 → 6 key is connected, and the branch chain points are connected by 1 → 2, 1 → 3 and 1 → 4 β- 1,3 / - 1,6 combined β- Glucan has the highest biological activity. With the different types and growth conditions of microorganisms, their structure and function are also different.
In the 1940s, Dr. pillemer first discovered and reported that there was a substance in the yeast cell wall that could improve immunity. Later, after further research by Dr. diluzio of Toulon University, it was found that the substance in yeast cell wall to improve immunity was a polysaccharide-- β- Glucan and isolated this substance from baker's yeast.
It was first found to have antitumor activity in 63 years, and then it was found to have antibacterial and immunomodulatory effects. It has unique biological activity in cancer, hepatitis, cardiovascular disease, diabetes, hypolipidemic and anti-aging.
Yeast glucan is the first glucan found to have immune activity.
Scientific research institutions such as Harvard University, Tulane University, the University of Washington and the Institute of radiobiology of the U.S. Air Force fermented and purified Agaricus blazei β- 1,3-glucan and studies have confirmed that natural yeast glucan has a unique targeting effect, which can directionally remove toxins in the body, and improve the phagocytic capacity of macrophages by more than 10 times, so that the human immune system can quickly achieve the best balance, without any toxic and side effects of drugs, and effectively prevent the occurrence of various chronic diseases.
On May 20, 2010, the announcement of the Ministry of health of the people's Republic of China No. 9 of 2010 issued by the Ministry of health recognized yeast β- Dextran is a new resource product.
β- The active structure of glucan is a polysaccharide composed of glucose units, most of which pass through β- 1,3 binding, which is the way of glucose chain connection. It can activate macrophages and neutrophils, so it can increase the content of leukocyte, cytokinin and special antibodies, comprehensively stimulate the body's immune system and repair damaged cells. Then, the body is more prepared to resist diseases caused by microorganisms. β- Glucan can quickly restore the ability of lymphocytes in the injured body to produce cytokines (IL-1) and effectively regulate the immune function of the body.
A large number of experiments show that, β- Glucan can promote the production of IgM antibody in vivo to improve the immune ability of body fluid. This glucan activated cell can stimulate the host non-specific defense mechanism, so its application has attracted much attention in tumor, infectious disease and trauma treatment. It is extracted by special steps in Agaricus blazei and does not contain endotoxin β- 1,3-glucan has been recognized as a safe substance by FDA and can be added to health food. Many reports show that mice take yeast orally β- 1,3-glucan can increase the phagocytosis of strong peritoneal cells.
Yeast glucan is a polysaccharide that exists in yeast cell wall and has immune enhancing activity-- β- Dextran. β- Glucan widely exists in various fungi and plants, such as Agaricus blazei, Lentinus edodes, Ganoderma lucidum and oats. It is the main functional substance for them to play a role in health care. Yeast glucan has stronger immune enhancing activity, and can improve blood lipid, eliminate toxins, resist radiation, repair cells and improve intestinal function.
Physiological Function
☆ eliminate toxins and enhance immune function. Yeast glucan can stimulate and enhance the phagocytic activity of immune cells such as NK cells and macrophages, stimulate the release of interleukin to enhance the ability of human body to resist harmful toxins, effectively enhance the ability of human body to remove toxins and improve human immunity;
☆ repair cells and resist radiation. The anti radiation effect of glucan is the result of promoting hematopoietic function. Yeast glucan can enhance the generative activity of blood cells, including granulocytes, monocytes and organ tissue cells, so as to recover the body cells damaged by lethal doses of radiation.
☆ regulate blood lipid. It is found that yeast glucan can significantly reduce the level of triglyceride, reduce the level of LDL (low density lipoprotein), and increase the level of HDL (high density lipoprotein), which can effectively prevent cardiovascular and cerebrovascular diseases such as coronary heart disease, arteriosclerosis and stroke;
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