Ceramides exist in all eukaryotic cells and play an important role in regulating cell differentiation, proliferation, apoptosis, aging and other life activities. Ceramide, as the main component of intercellular lipids in the cuticle of skin, not only acts as a second messenger molecule in the sphingomyelin pathway, but also plays an important role in the formation of the cuticle, maintaining skin barrier, moisturizing, anti-aging, whitening and disease treatment.
Studies have shown that ceramide can predict the risk of major cardiovascular diseases such as heart disease, stroke, revascularization, and death. In fact, patients with higher levels of ceramide in the blood are three times more likely to have cardiovascular disease than their peers, and have no relationship with low-density lipoprotein, cholesterol, or blockage of the heart's arteries.
The author of the article, Meeusen, believes that unlike the obstructive effects of cholesterol on blood vessels, ceramides are primarily aggravated by attracting inflammatory cells and promoting vascular closure. All cells have the ability to produce ceramides, but the accumulation of ceramides in the blood is mainly related to excess fat and excessive calorie intake.
Experimental studies show that ceramide plays an important role in maintaining skin barrier function.
The results showed that the content of ceramide was directly related to the dryness of skin. Ceramide can significantly enhance the adhesion between keratinocytes, improve the dryness of skin and reduce skin desquamation.
Ceramide has strong molecular ability of association water, which maintains skin moisture by forming a network structure in the cuticle. Therefore, neurophthalide has the function of keeping skin moisture.
Ceramide can improve skin dryness, desquamation and roughness; At the same time, ceramide can increase the thickness of cuticle, improve the water holding capacity of skin, reduce wrinkles, enhance skin elasticity and delay skin aging.
Some experimental studies have shown that ceramide has the function of regulating cell growth variation and inducing apoptosis.
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