Azelaic acid is an organic compound with the molecular formula of c9h16o4. Its appearance is white to yellowish monoclinic prism, acicular crystal or powder. It is used as plasticizer and in alkyd resin, paint and chemical synthesis. Irritating to skin, eyes, mucous membrane and upper respiratory tract. Inhalation or ingestion is harmful to the body. It is harmful to the environment and can cause pollution to water and atmosphere.
Purpose
1. It is mainly used to produce dioctyl azelaic acid plasticizer, and can also be used as raw materials for the production of spices, lubricants, oil agents and polyamide resins.
2. Rhododendron acid has antibacterial property and can be used as food preservative. The use of gargle is conducive to the prevention and treatment of dental caries, and the use of soap can avoid the cracking of the soap surface. It has good permeability to the skin. The use in cream cosmetics can increase the absorption function of the skin. It has a variety of effects and can be used in skin plaster. It has the functions of brightening and whitening. Rhododendron acid or its zinc salt is used in combination with Vitamin B6 for hair care products. It is suitable for the treatment of male hormonal alopecia with strong male endocrine and stimulates hair growth at the same time.
This product also has anti proliferative and anti cytotoxic effects, which seems to be by destroying mitochondrial respiration and cellular DNA synthesis, rather than inhibiting tyrosinase activity. UV structural study showed that when melanoma cells of skin or choroid or skin biopsy tissues from patients with malignant small nevus or skin melanoma were placed in Rhododendron acid (≤ 100 nmol / L) in vitro, there were selective and obvious mitochondrial expansion, vacuole formation and accumulation of cytoplasmic lipid particles.
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