1. What is Celastrol Powder?
Celastrol is a natural product with a variety of biological activities, derived from the root bark of the traditional Chinese medicine Tripterygium wilfordii. Tripterygium wilfordii, also known as celastrus wilfordii, has a strong Antioxidant effect, anti-cancer neovascularization effect, anti-rheumatoid effect, mainly from the root bark of the celastraceae plant Tripterygium wilfordii, which is one of the effective ingredients of preparations such as tripterygium wilfordii tablets and tripterygium glycosides tablets for the treatment of rheumatoid diseases.
2. Main activities and pharmacological actions
(1). Celastrol Powder has immunomodulatory effect. It can significantly inhibit the formation of hemolytic plaque cells in spleen cells. It can significantly inhibit delayed hypersensitivity.
(2). Anti-inflammatory effect of Tripterygium wilfordii extract.
(3). Tripterygium wilfordii Extract has an anti-oxidation effect 15 times that of tocopherol, inhibits the peroxidation inside and outside the mitochondrial membrane, and directly removes free radicals.
(4). Tripterygium wilfordii can prolong sleep time.
(5). It has immunosuppressive effect: it inhibits the proliferation of spleen cells and lymphocytes.
(6). Inhibition of sperm fertilization ability,
(7). Celastrol 98% has anti-arthritis effect.
3. Application
(1). Used for content determination/identification/pharmacological experiment, etc.
(2). Pharmacological effect: It has strong antioxidant effect, anti-cancer neovascularization effect and anti-rheumatoid effect.
(3). An effective proteasome inhibitor that can induce cancer cell apoptosis by inhibiting proteasome activity.
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